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L-2-Hydroxyglutaric acid
Item number: TGM-T13749-10mg
Description: L-2-Hydroxyglutaric acid, an epigenetic modifier and potential oncometabolite in renal cancer, impedes mitochondrial creatine kinase (Mi-CK) activity, exhibiting Km and Ki values of 2.52 mM and 11.13 mM, respectively. Additionally, it obstructs histone demethylases, thereby encouraging histone...
| Keywords: | (S)-2-Hydroxyglutaric acid |
| Application: | Metabolite |
| CAS | 13095-48-2 |
| MW: | 148.11 D |
From 77.00€
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L-alpha-Hydroxyglutaric Acid
Item number: Cay21123-10
L-alpha-Hydroxyglutaric acid (L-2-HG) is an alpha-hydroxy acid. It is metabolized to 2-oxoglutarate (alpha-ketoglutarate) by L-2-hydroxyglutarate dehydrogenase, and mutations in this enzyme lead to 2-hydroxyglutaric aciduria, a neurometabolic disorder characterized by increased L-2-HG levels. L-2-HG is structurally...
| Keywords: | 2(S)-HG, 2(S)-Hydroxyglutaric Acid, L-2-HG, L-2-Hydroxyglutaric Acid, 2S-hydroxy-pentanedioic acid |
| Application: | Metabolite |
| CAS | 13095-48-2 |
| MW: | 148.1 D |
From 44.00€
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