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Item number: Cay11479-10

Bindarit is an inhibitor of monocyte chemoattractant protein (MCP) production that is selective for MCP-1/CCL2, MPC-3/CCL7, and MCP-2/CCL8 over other chemokines. It inhibits LPS- or C. albicans-induced production of MCP-1/CCL2 in isolated human monocytes (IC50s = 172 and 403 µM, respectively). Bindarit downregulates...

Keywords:	AF 2838, 2-methyl-2-[[1-(phenylmethyl)-1H-indazol-3-yl]methoxy]-propanoic acid
Application:	Monocyte chemotactic protein synthesis inhibitor
CAS	130641-38-2
MW:	324.4 D

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Bindarit

Item number: TGM-T6413-10mg

Description: Bindarit (AF2838) displays specific inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8. Target: CCR. Smiles: CC(C)(OCc1nn(Cc2ccccc2)c2ccccc12)C(O)=O. References: Zoja C, et al. Kidney Int, 1998, 53(3), 726-734.

Keywords:	AF2838
Application:	Targets C-C motif chemokine 2 (CCL2, MCP1)
CAS	130641-38-2
MW:	324.37 D

From 33.00€ *

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