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Item number: Cay34977-1

N-desmethyl Diltiazem is an active metabolite of the calcium channel inhibitor diltiazem. It is formed from diltiazem by the cytochrome P450 (CYP) isoforms CYP3A4, CYP3A5, and CYP3A7. N-desmethyl Diltiazem binds to isolated rat cerebral cortex homogenates (IC50 = 323 nM) and inhibits spontaneous contractions in...

Keywords:	3-(acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-1,5-benzothiazepin-4(5H)-one, monohydrochloride
Application:	Diltiazem active metabolite
CAS	130606-60-9
MW:	437 D

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