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Item number: Cay13946-100

Pamoic acid is a potent agonist of GPR35 orphan receptors (EC50 = 79 nM in a beta-arrestin recruitment assay). It induces GPR35 translocation from the plasma membrane to the cytoplasm with an EC50 value of 22 nM. Pamoic acid also increases ERK1/2 phosphorylation in a concentration-dependent manner in U20S cells...

Keywords:	Embonic Acid, NSC 30188, NSC 40132, 4,4'-methylenebis[3-hydroxy-2-naphthalenecarboxylic acid]
Application:	Potent GPR35 agonist
CAS	130-85-8
MW:	388.4 D

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