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TNP-470
TNP-470

Item number: TGM-T17110-10mg

Description: TNP-470 is a methionine aminopeptidase-2 inhibitor and an angiogenesis inhibitor. Target: Others. Smiles: [H][C@@]1([C@H](OC)[C@@H](CC[C@]11CO1)OC(=O)NC(=O)CCl)[C@@]1(C)O[C@@H]1CC=C(C)C
Keywords: AGM-1470
Application: Synthetic fumagillin analog, irreversible MetAP2 inhibitor, angiogenesis inhibitor
CAS 129298-91-5
MW: 401.88 D
From 228.00€ *
Review
TNP-470
TNP-470

Item number: Cay16449-10

TNP-470 is a synthetic analog of fumagillin (Cay-11332) that inhibits angiogenesis. It irreversibly inactivates methionine aminopeptidase-2 (MetAP2, IC50 = 2 µM), blocking endothelial cell proliferation in vitro and angiogenesis in vivo. It is without effect on MetAP1. TNP-470 has therapeutic potential in cancer and...
Keywords: AGM-1470, NSC 642492, O-(Chloroacetyl-carbamoyl) Fumagillol,...
Application: Synthetic fumagillin analog, irreversible MetAP2 inhibitor, angiogenesis inhibitor
CAS 129298-91-5
MW: 401.9 D
From 125.00€ *
Review