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DPQ
DPQ

Item number: Cay14450-1

The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. DPQ is a potent inhibitor of PARPs, inhibiting PARP1 with an IC50 value of 40 nM. It is approximately 10-fold less potent against PARP2. DPQ can...
Keywords: PARP Inhibitor III, 3,4-dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone
Application: PARP inhibitor
CAS 129075-73-6
MW: 302.4 D
From 84.00€ *
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DPQ
DPQ

Item number: AG-CR1-0037-M001

Very potent PARP-1 inhibitor.
Keywords: 3,4-Dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone
Application: PARP-1 inhibitor
CAS 129075-73-6
MW: 302,4 D
From 55.00€ *
Review
DPQ
DPQ

Item number: TGM-T60695-100mg

Description: DPQ is a potent inhibitor of PARP-1 that can be used in neuroprotection research. DPQ reduce the PARP activation induced by N-methyl-d-aspartate (NMDA), restoring ATP to near control levels as well as significantly attenuating neuronal injury in the severe NMDA exposure model [1]. Target: Others....
Application: PARP-1 inhibitor
CAS 129075-73-6
MW: 302.41 D
From 896.00€ *
Review