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Item number: Cay36502-1

PF-04753299 is an inhibitor of LpxC (IC50 = 1.37 nM), a bacterial deacetylase involved in the biosynthesis of LPS lipid A. It is selective for LpxC over a panel of 16 human matrix metalloproteinases (MMPs, Kis = >1 µM for all). PF-04753299 is active against P. aeruginosa, K. pneumoniae, E. coli, E. aerogenes, C....

Keywords:	N-hydroxy-alphaR-methyl-alpha-(methylsulfonyl)-[1,1'-biphenyl]-4-butanamide
Application:	LpxC inhibitor
CAS	1289620-49-0
MW:	347.4 D

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PF-04753299

Item number: TGM-T41275-10mg

Description: PF-04753299 is a potent and selective inhibitor of UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC), demonstrating bactericidal effects against gonococcal isolates and exhibiting inhibitory activity against E. coli, P. aeruginosa, and K. pneumoniae, with minimum inhibitory...

Application:	LpxC inhibitor
CAS	1289620-49-0
MW:	347.43 D

From 65.00€ *

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