2 products were found matching "1287761-01-6"!
No results were found for the filter!
PTUPB
Item number: TGM-T12580-100mg
Description: PTUPB is a potent dual inhibitor of sEH and COX-2 enzymes with IC50 values of 0.9 nM and 1.26 µM, respectively. Target: COX, Epoxide Hydrolase. Smiles: NS(=O)(=O)c1ccc(cc1)-n1nc(CCCNC(=O)Nc2ccc(cc2)C(F)(F)F)cc1-c1ccccc1. References: Sun CC, et al. PTUPB ameliorates high-fat diet-induced non-alcoholic...
| Application: | SEH / COX-2 dual inhibitor |
| CAS | 1287761-01-6 |
| MW: | 543.56 D |
From 74.00€
*
PTUPB
Item number: Cay10897-1
PTUPB is a dual inhibitor of soluble epoxide hydrolase (sEH) and COX-2 (IC50s = 0.009 and 1.26 µM, respectively). It is selective for sEH and COX-2 over COX-1 (IC50 = >100 µM). PTUPB (10 mg/kg) increases latency to paw withdrawal in the von Frey mechanical assay in a rat model of LPS-induced inflammatory pain. It...
| Keywords: | 4-[5-phenyl-3-[3-[[[[4-(trifluoromethyl)phenyl]amino]carbonyl]amino]propyl]-1H-pyrazol-1-yl]-benzenesulfonamide |
| Application: | SEH / COX-2 dual inhibitor |
| CAS | 1287761-01-6 |
| MW: | 543.6 D |
From 130.00€
*
