Description: Gingerenone A is an effective Nrf2-Gpx4 activator. It is a small molecule compound isolated from ginger. It has anti-cancer activity, can prolong the cell cycle of cancer cells, and can inhibit dextran sodium sulfate (DSS)-induced colitis. Ferroptosis in secondary liver injury (SLI) in mice. Target:...

Gingerenone A is a diarylheptanoid and polyphenol that has been found in Z. officinale and has diverse biological activities. It inhibits tyrosinase (IC50 = 9.4 µM for the mushroom enzyme) and scavenges DPPH (Cay-14805) radicals in a cell-free assay (IC50 = 12.6 µM). Gingerenone A (5 and 10 µM) also inhibits JAK2...