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Chroman 1
Item number: TGM-T14960-100mg
Description: Chroman 1 is a potent inhibitor of ROCK1 (IC50 = 52 pM) and ROCK2 (IC50 = 1 pM). Target: ROCK. Smiles: COc1ccc2OC[C@H](Cc2c1)C(=O)Nc1ccc(cc1OCCN(C)C)-c1cn[nH]c1. References: Yen Ting Chen, et al. Asymmetric synthesis of potent chroman-based Rho kinase (ROCK-II) inhibitors. Med.Chem.Commun., 2011, 2, 73-75.
| Application: | ROCK2 inhibitor |
| CAS | 1273579-40-0 |
| MW: | 436.5 D |
From 71.00€
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Chroman 1
Item number: Cay38248-1
Chroman 1 is an inhibitor of Rho-associated kinase 2 (ROCK2, IC50 = 50s = 1,740 and 127 nM, respectively). Chroman 1 inhibits the phosphorylation of myosin light-chain (MLC) in a cell-based assay (IC50 = 98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble. lambdamax: 273, 300 nm....
| Keywords: | (S)-Chroman 1,... |
| Application: | ROCK2 inhibitor |
| CAS | 1273579-40-0 |
| MW: | 436.5 D |
From 67.00€
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