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(R)-(-)-JQ1 Enantiomer
Item number: TGM-T19618-100mg
Description: (R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1, a BET bromodomain inhibitor, which acts on BRD4(1/2) with IC50 values of 77 nM and 33 nM in a cell-free assay. Target: Epigenetic Reader Domain. Smiles: Cc1nnc2[C@@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1
| CAS | 1268524-71-5 |
| MW: | 456.99 D |
From 40.00€
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(-)-JQ1
Item number: Cay11232-1
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. (±)-JQ1...
| Keywords: | (6R) 4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid,... |
| Application: | Gene Regulation studies |
| CAS | 1268524-71-5 |
| MW: | 457 D |
From 44.00€
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