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Item number: TGM-T4229-100mg

Description: S1RA hydrochloride (E-52862 hydrochloride) is an effective and specific sigma-1 receptor(sigma1R, Ki: 17 nM) antagonist, and has good selectivity against sigma2R (Ki > 1000 nM). Target: Sigma receptor. Smiles: Cl.Cc1cc(OCCN2CCOCC2)nn1-c1ccc2ccccc2c1. References: Díaz JL, et al. Synthesis and biological...

Keywords:	E-52862 hydrochloride
Application:	sigma1 receptor antagonist
CAS	1265917-14-3
MW:	373.87 D

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S1RA (hydrochloride)

Item number: Cay32729-1

S1RA is a sigma-1 (sigma1) receptor antagonist (Ki = 17 nM). It is selective for sigma1 receptors over sigma2 receptors (Ki = 9,300 nM), as well as a panel of 170 additional receptors at 1 µM. S1RA reduces capsaicin-induced mechanical allodynia, formalin-induced licking and biting behavior, and partial sciatic nerve...

Keywords:	E-52862, P 027, 4-[2-[[5-methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl]oxy]ethyl]-morpholine, monohydrochloride
Application:	sigma1 receptor antagonist
CAS	1265917-14-3
MW:	373.9 D

From 44.00€ *

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