Althiomycin is a polyketide synthase-derived thiazole antibiotic originally isolated from S. althioticus. It is active against Gram-positive bacteria, including S. aureus, S. epidermidis, and S. pyogenes (MICs = 25, 25, and 3.1 µg/ml, respectively). Althiomycin inhibits protein synthesis in E. coli when used at...

Description: Althiomycin is an antibiotic. Target: Others. Smiles: COC1=CC(=O)N(C1)C(=O)[C@H]1CSC(=N1)C(CO)NC(=O)c1csc(\C=N\O)n1 , c:14,t:2, . References: Gerc AJ, Song L, Challis GL, Stanley-Wall NR, Coulthurst SJ. The insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide...