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Ciclesonide
Item number: LKT-C324091.100
Ciclesonide is an anti-inflammatory corticosteroid. Its active metabolite and several ciclesonide-acetal derivatives have been found to block RNA replication of the SARS-Cov-2 virus. Ciclesonide also inhibits lung cancer stem cells through Hedgehog signaling-mediated SOX2 regulation. Solubility: Insoluble in water....
| Keywords: | Alvesco, Omnaris, Zetonna, RPR251526, (R)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal... |
| Application: | Corticosteroid |
| CAS | 126544-47-6 |
| MW: | 540.7 D |
From 138.00€
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Ciclesonide
Item number: Cay18227-1
Ciclesonide (CIC) is a prodrug form of the glucocorticoid receptor agonist desisobutyryl-CIC (des-CIC). CIC binds to the glucocorticoid receptor with a Ki value of 37 nM. It is selective for the glucocorticoid receptor over the estrogen, progesterone, and testosterone receptors. CIC inhibits eosinophil influx into...
| Keywords: | CIC, RPR 251526,... |
| Application: | Glucocorticoid receptor agonist |
| CAS | 126544-47-6 |
| MW: | 540.7 D |
From 44.00€
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Ciclesonide
Item number: TGM-T2526-100mg
Description: Ciclesonide (Alvesco)(RPR251526) is a glucocorticoid used for the treatment of obstructive airway diseases. Target: Glucocorticoid Receptor. Smiles: C(COC(C(C)C)=O)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(O[C@H](O2)[C@@H]4CCCCC4)[H])([C@]5([C@]([C@@H](O)C3)([C@]6(C)C(CC5)=CC(=O)C=C6)[H])[H])[H]. References: Guo...
| Keywords: | Alvesco, RPR251526, Omnaris, Zetonna |
| Application: | Targets glucocorticoid receptor (NR3C1, GR) |
| CAS | 126544-47-6 |
| MW: | 540.69 D |
From 45.00€
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