2 products were found matching "1263774-59-9"!

No results were found for the filter!

Item number: TGM-T15096-100mg

Description: Delgocitinib (JTE-052) is a specific JAK (Janus kinase) inhibitor with IC50 values of 2.8, 2.6, 13, and 58 nM for JAK1, JAK2, JAK3, and Tyk2 respectively. Delgocitinib is involved in various inflammatory and autoimmune diseases through JAK-dependent cytokines and can effectively suppress multiple...

Keywords:	Corectim(Delgocitinib), JTE-052
Application:	Targets Janus kinase 1 [EC:2.7.10.2] (JAK1)
CAS	1263774-59-9
MW:	310.35 D

From 172.00€ *

Show details

Review

Delgocitinib

Item number: Cay38307-1

Delgocitinib is an inhibitor of JAK1, JAK2, JAK3, and tyrosine kinase 2 (TYK2, IC50s = 2.8, 2.6, 13, and 58 nM, respectively). It is selective for JAK1, JAK2, JAK3, and TYK2 over lymphocyte cell-specific tyrosine kinase (LCK, IC50 = 5,800 nM). Delgocitinib inhibits IL-31-induced increases in STAT3 phosphorylation...

Keywords:	JTE-052, (3S,4R)-3-methyl-beta-oxo-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octane-1-propanenitrile
Application:	JAK1 / JAK2 / JAK3 / TYK2 inhibitor
CAS	1263774-59-9
MW:	310.4 D

From 106.00€ *

Show details

Review

Didn't find the right Product? Here are some useful Search Tips!

Checklist-Thumbnail

All our products have English titles and descriptions. Therefore, use English search terms.
Write out Greek letters - i.e. "alpha" instead of α or "beta" instead of β.
Do not add "and" when entering multiple search terms.
Use the singular (e.g. "antibody" instead of "antibodies").
If available, try synonyms (e.g. for a specific protein).
You can search for chemical substances using the unique CAS number (Chemical Abstracts Service).
In addition, you can also use the UniProt or KEGG accession number for the product search.
Use our filter function to narrow down your search results. If you want to remove a selected filter again, click on the small "x" next to the filter.
Are you looking for products from a specific supplier? Then enter the corresponding supplier name and select it in the appearing suggestion field. Alternatively, you can also use our supplier overview.
Use - if known - the specific product number. Especially for short numbers, note the supplier code in front of each number for most of our partners (e.g. for AAT Bioquest "ABD-121" instead of just "121"). Click on the button below to find all supplier codes and additional information.

All Supplier Codes

We would be very happy to support you in your product search! Contact us at info@biomol.com.