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Item number: Cay29665-10

Cenerimod is a sphingosine-1-phosphate receptor 1 (S1P1) modulator with an EC50 value of 1 nM in a [35S]GTP?S binding assay. It is selective for S1P1 over S1P2, -3, -4, and -5 (EC50s = >10,000, 228, 2,137, and 36 nM, respectively). Cenerimod (5 µM) decreases TGF-beta-induced increases in collagen levels in primary...

Keywords:	(2S)-3-[4-[5-(2-cyclopentyl-6-methoxy-4-pyridinyl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-1,2-propanediol
Application:	Sphingosine-1-phosphate receptor 1 (S1P1) modulator
CAS	1262414-04-9
MW:	453.5 D

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Cenerimod

Item number: TGM-T14924-10mg

Description: Cenerimod (ACT-334441) is an orally active, selective, and potent sphingosine 1-phosphate receptor (S1P1) agonist (EC50: 1 nM).Cenerimod inhibits multiple S1P isoforms and can be used to study murine experimental autoimmune encephalomyelitis (EAE) and murine scleroderma. Target: S1P Receptor. Smiles:...

Keywords:	ACT-334441
Application:	Targets sphingosine 1-phosphate receptor 1 (S1PR1, EDG1, CD363)
CAS	1262414-04-9
MW:	453.53 D

From 34.00€ *

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