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Item number: TGM-TP1946-5mg

Description: Tripeptide substance P (SP) antagonist (IC50 = 90 µM). Also inhibits binding of SP to Mas-related GPCR (MRGPR) X2. Inhibits SP-induced IgE-independent degranulation of mast cells in vitro. Inhibits compound 48/80-induced MRGPRX2 activation and scratching in mice in vivo. References: Hagiwara et al...

CAS	126088-82-2
MW:	697.78 D

723.00€ *

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