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Item number: Cay19699-5

Birinapant is a bivalent mimetic of the Diablo homolog known as second mitochondria-derived activator of caspase (Smac). It is an antagonist of cellular inhibitor of apoptosis 1 (cIAP1, or BIRC2), cIAP2 (BIRC3), and XIAP (BIRC4), binding each at nanomolar concentrations. Birinapant causes rapid cIAP1 degradation,...

Keywords:	TL-32711,...
Application:	Antineoplastic, XIAP / cIAP1 inhibitor
CAS	1260251-31-7
MW:	806.9 D

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TL-32711

Item number: LKT-T4400.10

TL-32711 is a Smac mimetic that is currently in clinical trials as a potential treatment for a variety of cancers. TL-32711 inhibits members of the inhibitor of apoptosis protein (IAP) family proteins, inducing degradation of cIAP1 and cIAP2. TL-32711 exhibits anticancer chemotherapeutic activity, inhibiting...

Keywords:	Birinapant
Application:	Antineoplastic, Smac mimetic
CAS	1260251-31-7
MW:	806.94 D

From 90.00€ *

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