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Vonoprazan (fumarate)
Item number: Cay24200-500
Vonoprazan is a selective, reversible, and potassium-competitive proton pump inhibitor that inhibits gastric H+/K+ ATPase (IC50 = 17 nM) but does not inhibit porcine Na+/K+ ATPase activity when used at a concentration of 10 µM. It maintains its inhibitory effect in both weakly acidic (pH 6.5) and neutral (pH 7.5)...
| Keywords: | TAK-438, 5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine, 2-butenedioate |
| Application: | Proton pump inhibitor |
| CAS | 1260141-27-2 |
| MW: | 461.5 D |
From 69.00€
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Vonoprazan fumarate
Item number: TGM-T2404-1mL
Description: Vonoprazan fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase. Target: ATPase. Smiles: CNCc1cn(c(c1)c1ccccc1F)S(=O)(=O)c1cnccc1.C(=C\C(=O)O)/C(=O)O. References: Arikawa Y, et al. J Med Chem, 2012, 55(9), 4446-4456.
| Keywords: | TAK-438 |
| CAS | 1260141-27-2 |
| MW: | 461.46 D |
From 39.00€
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