3 products were found matching "1259296-46-2"!
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HDAC6 Inhibitor
Item number: Cay15200-10
HDAC6 is a predominantly cytoplasmic enzyme that targets alpha-tubulin, cortactin, and heat shock protein 90, as well as other substrates. In this way, it impacts development, proliferation, invasion, and tumorigenesis. HDAC6 Inhibitor is a potent and selective inhibitor of HDAC6 (IC50 = 36 nM) that poorly blocks...
| Keywords: | Histone Deacetylase 6, 1,2,3,4-tetrahydro-N-hydroxy-2-[(1-methyl-1H-pyrrol-2-yl)carbonyl]-6-isoquinolinecarboxamide |
| Application: | Cell-permeable HDAC6 inhibitor |
| CAS | 1259296-46-2 |
| MW: | 299.3 D |
From 77.00€
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I-BET762
Item number: SYN-3033-M100
I-BET762 (GSK525762A) is an inhibitor for BET (bromodomain and extra terminal domain) proteins, BRD2, BRD3 and BRD4. It binds to the tandem bromodomains of BET with a Kd of 50.5-61.3nM, displaces a tetra-acetylated H4 peptide prebound to tandem bromodomains of BET with IC50 of 32.5-42.5nM in FRET analysis. I-BET762...
| Keywords: | GSK-525762A |
| Application: | BET (bromodomain and extra terminal domain) protein BRD2 / BRD3 / BRD4 inhibitor |
| CAS | 1259296-46-2 |
| MW: | 423.9 D |
Please request pricing for this article.
MPI_5a
Item number: SYN-3040-M001
Solid. Soluble in DMSO. MPI_5a is a potent selective inhibitor of HDAC6. HDAC6 is a predominantly cytoplasmic enzyme that targets alpha-tubulin, cortactin and heat shock protein 90, and other substrates. MPI-5a has an IC50 of 36nM in tumour cell models and inhibits the acetylation of tubulin in cells with an IC50...
| Keywords: | MPI5a, N-Hydroxy-2-(1-methyl-1H-pyrrole-2-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide |
| Application: | HDAC6 inhibitor |
| CAS | 1259296-46-2 |
| MW: | 299,3 D |
From 106.00€
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