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Item number: Cay30937-1

AC-265347 is a calcimimetic and positive allosteric modulator of the calcium-sensing receptor (CaSR, EC50 = 7.94 nM in a cell-based phosphatidylinositol hydrolysis assay in the presence of calcium)., It inhibits the proliferation of NIH3T3 cells expressing human CaSR (EC50 = 25.12 nM). AC-265347 reduces plasma...

Keywords:	alpha-(2,4-dimethylphenyl)-alpha-methyl-2-benzothiazolemethanol
Application:	Calcimimetic, positive allosteric CaSR modulator
CAS	1253901-26-6
MW:	283.4 D

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AC265347

Item number: TGM-T29541-100mg

Description: AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity that inhibits neuroblastoma tumour growth by inducing differentiation.AC265347 can be used to study neuroblastoma. Target: CaSR. Smiles: OC(C1=NC=2C=CC=CC2S1)(C3=CC=C(C=C3C)C)C....

Keywords:	AC-265347
CAS	1253901-26-6
MW:	283.39 D

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