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Losartan (potassium salt)
Item number: Cay10006594-10
Losartan is an antagonist of angiotensin II type 1b (AT1b) receptor (IC50 = 2.2 nM in COS-7 cells expressing the rat receptor). It reduces U-46619-induced aggregation of platelets in isolated human platelet-rich plasma when used at a concentration of 5 µM. It decreases 1-lipoxygenase (1-LO) levels in the endothelial...
| Keywords: | DuP-753, MK 954, 2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol,... |
| Application: | AT1 receptor antagonist |
| CAS | 124750-99-8 |
| MW: | 461 D |
From 26.00€
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Losartan Potassium
Item number: LKT-L5873.1
AT1 antagonist.
| Keywords: | DuPont-753, Losaprex, Lortaan, Neo-Lotan, Oscaar, 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-... |
| Application: | Angiotensin II receptor type 1 (AT1) antagonist |
| CAS | 124750-99-8 |
| MW: | 461.01 D |
From 91.00€
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Losartan potassium
Item number: TGM-T0215-1g
Description: Losartan potassium (DuP-753 potassium), an Angiotensin II Receptor Blocker, selectively and competitively inhibits the binding of angiotensin II to the angiotensin I (AT1) receptor. Target: RAAS. Smiles: [K+].CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[n-]1. References: Burnier, M. Angiotensin II type...
| Keywords: | MK 954, DuP-753 potassium, DuP 753 |
| CAS | 124750-99-8 |
| MW: | 461.01 D |
From 32.00€
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