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VS-5584
VS-5584

Item number: Cay16294-1

Phosphatidylinositol 3-kinase (PI3K) signaling through Akt/PKB and the mammalian target of rapamycin (mTOR) controls gene expression related to cell proliferation, differentiation, and apoptosis. Increased activity of this pathway is important in many types of cancer. VS-5584 is a purine analog that inhibits mTOR...
Keywords: 5-[8-methyl-9-(1-methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-2-pyrimidinamine
Application: mTOR / PI3K inhibitor
CAS 1246560-33-7
MW: 354.4 D
From 49.00€ *
Review
VS-5584
VS-5584

Item number: LKT-V7200.1

VS-5584 inhibits PI3K and displays anticancer chemotherapeutic activity, inhibiting cell proliferation in a variety of cancer cell lines and suppressing tumor growth in animal models of gastric cancer.
Application: mTOR / PI3K inhibitor
CAS 1246560-33-7
MW: 354.41 D
From 109.00€ *
Review
VS-5584
VS-5584

Item number: TGM-T6103-100mg

Description: VS-5584 (SB2343) is a pan-PI3K/mTOR kinase inhibitor. Target: PI3K, mTOR. Smiles: CC(C)n1c(C)nc2c(nc(nc12)N1CCOCC1)-c1cnc(N)nc1. References: JA Pachter, et al. Molecular Targets and Cancer Therapeutics, 2012, abstract 405.
Keywords: SB2343 , VS 5584 , VS5584
Application: mTOR / PI3K inhibitor
CAS 1246560-33-7
MW: 354.41 D
From 30.00€ *
Review