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MPI-0479605
MPI-0479605

Item number: SYN-1187-M001

Soluble in DMSO. MPI-0479605 inhibits TTK kinase activity in vitro with an IC(50) of 4nM.
Keywords: MPI0479605
Application: TTK inhibitor
CAS 1246529-32-7
MW: 444,0 D
From 250.00€ *
Review
MPI-0479605
MPI-0479605

Item number: Cay22136-1

MPI-0479605 is a potent and ATP-competitive inhibitor of the mitotic kinase MPS1 (IC50 = 1.8 nM). It is selective for MPS1 over a panel of 79 kinases at a concentration of 500 nM. MPI-0479605 induces time-dependent degradation of cyclin B and securin and decreases phosphorylation of BUBR1 resulting in failed...
Keywords: N6-cyclohexyl-N2-[2-methyl-4-(4-morpholinyl)phenyl]-9H-purine-2,6-diamine
Application: TTK inhibitor
CAS 1246529-32-7
MW: 407.5 D
From 77.00€ *
Review