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VU0364739
Item number: Cay42914-1
VU036739 is an inhibitor of phospholipase D2 (PLD2, IC50 = 20 nM). It is selective for PLD2 over PLD1 (IC50 = 1,500 nM). VU036739 (10 µM) induces apoptosis in MDA-MB-231 breast cancer cells. It decreases levels of deoxyribonucleoside triphosphates in serum-starved U87MG glioma cells when used at a concentration of 5...
| Keywords: | N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-2-naphthalenecarboxamide |
| Application: | Phospholipase D2 (PLD2) inhibitor |
| CAS | 1244639-78-8 |
| MW: | 446.53 D |
From 76.00€
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VU0364739
Item number: TGM-T78161-50mg
Description: VU0364739, a selective phospholipase D2 (PLD2) inhibitor with an IC50 of 22 nM, effectively reduces cancer cell proliferation [1]. Target: Phospholipase. Smiles: O=C(NCCN1CCC2(C(=O)NCN2C=3C=CC=C(F)C3)CC1)C=4C=CC=5C=CC=CC5C4
| CAS | 1244639-78-8 |
| MW: | 446.52 D |
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