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Item number: TGM-T15769-100mg

Description: LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2. Target: IL Receptor. Smiles: CCCCCC(=C)[C@@H](O)[C@H](C)C(=O)N1[C@H](COC1=O)C(C)C. References: Hong SS, et al. A Novel Small-Molecule Inhibitor Targeting the IL-6 Receptor beta Subunit,...

Application:	gp130 (CD130)-IL6/IL6Ralpha protein-protein interaction inhibitor
CAS	1239600-18-0
MW:	311.42 D

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LMT-28

Item number: Cay40837-10

LMT-28 is an inhibitor of the protein-protein interaction between glycoprotein 130 (gp130) and the IL-6-bound form of IL-6 receptor subunit alpha (IL-6Ralpha). It binds to gp130 (Kd = 7.4 µM) and selectively inhibits IL-6-induced STAT3 phosphorylation over leukemia inhibitor factor- or phorbol 12-myristate...

Keywords:	(4S)3-[(2S,3S)-3-hydroxy-2-methyl-4-methylene-1-oxononyl]-4-(1-methylethyl)-2-oxazolidinone
Application:	gp130 (CD130)-IL6/IL6Ralpha protein-protein interaction inhibitor
CAS	1239600-18-0
MW:	311.4 D

From 92.00€ *

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