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11S(12R)-EET
Item number: Cay9004348-100
11S(12R)-EET is an oxylipin and a metabolite of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). It is selectively formed from arachidonic acid by the cytochrome P450 (CYP) isoform CYP2B2 over CYP2C23 and CYP2C24, as well as CYP2C9 over CYP2C8. 11S(12R)-EET (50 nM) activates large-conductance...
| Keywords: | 11S(12R)-EpETrE, 11S(12R)-epoxy-5(Z),8(Z),14(Z)-ETrE, 11S(12R)-epoxy-all-cis-5,8,14-Eicosatrienoic Acid,... |
| Application: | Oxylipin, arachidonic acid metabolite |
| CAS | 123931-40-8 |
| MW: | 320.5 D |
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(±)11(12)-EET
Item number: TGM-T35494-1mg
Description: (±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3] A higher proportion of 11(R),12(S)-EET is produced by the CYP450 isoforms CYP2C23 and CYP2C24, while CYP2B2 produces a higher proportion of 11(S),12(R)-EET.[3]...
| CAS | 123931-40-8 |
| MW: | 320.473 D |
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