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QNZ 46
QNZ 46

Item number: Cay14857-1

QNZ 46 is an antagonist of NR2C- and NR2D-subunit containing NMDA receptors (IC50s = 6 and 3 µM, respectively, for receptors expressed in Xenopus oocytes). It is selective for NR2C- and NR2D-subunit containing NMDA receptors over receptors containing NR2A and NR2B subunits as well as over the AMPA receptor GluR1...
Keywords: 4-[6-methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)-quinazolinyl]-benzoic acid
Application: NR2C/NR2D-selective NMDA receptor non-competitive antagonist
CAS 1237744-13-6
MW: 443.4 D
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QNZ46
QNZ46

Item number: TGM-T2362-100mg

Description: QNZ46 is a non-competitive antagonist of NMDA receptors, selectively targeting NR2C/NR2D subunits. Target: iGluR, NMDAR. Smiles: COc1ccc2nc(\C=C\c3cccc(c3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1. References: Hansen KB, et al. J Neurosci. 2011 Mar 9,31(10):3650-3661.
CAS 1237744-13-6
MW: 443.41 D
From 29.00€ *
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