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Leucomethylene blue mesylate
Item number: TGM-T7003-100mg
Description: Leucomethylene blue mesylate (TRx0237 mesylate) is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia. Target: Microtubule Associated, Beta Amyloid. Smiles: CS(O)(=O)=O.CS(O)(=O)=O.CN(C)c1ccc2Nc3ccc(cc3Sc2c1)N(C)C. References:...
| Keywords: | TRx0237 mesylate, Leucomethylene Blue Dimesylate, Methylene blue leuco base mesylate salt, TRx0237 (LMTX) mesylate |
| Application: | Targets microtubule-associated protein tau (MAPT, TAU) |
| CAS | 1236208-20-0 |
| MW: | 477.62 D |
From 49.00€
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TRx0237 (mesylate)
Item number: Cay34307-5
TRx0237 is an inhibitor of tau aggregation. It inhibits tau-tau binding (IC50 = 238 µM) and tau aggregation in 3T6H cells expressing human tau (EC50 = 0.19 µM). TRx0237 (5 and 15 mg/kg) increases hippocampal acetylcholine (ACh) and synaptophysin levels, as well as increases mitochondrial complex IV activity,...
| Keywords: | Hydromethylthionine, Leucomethylene Blue, Leukomethylthioninium dihydromesylate, LMTM,... |
| Application: | Tau aggregation inhibitor |
| CAS | 1236208-20-0 |
| MW: | 477.6 D |
From 78.00€
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