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Item number: Cay44272-10

TUG-469 is an agonist of free fatty aid receptor 1 (FFAR1/GPR40). It induces calcium mobilization in a reporter assay using cells expressing human FFAR1/GPR40 (EC50 = 18. nM). TUG-469 (10 µM) induces insulin secretion in INS-1E insulinoma cells. It inhibits increases in blood glucose levels in a glucose tolerance...

Keywords:	4-[[(2'-methyl[1,1'-biphenyl]-3-yl)methyl]amino]-benzenepropanoic acid
Application:	FFAR1/GPR40 agonist
CAS	1236109-67-3
MW:	345.44 D

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TUG-469

Item number: TGM-T34967-25mg

Description: TUG-469 is an agonist of free fatty acid 1(FFA) receptor. Target: GPR. Smiles: Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1. References: Panse M, et al. Activation of extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) by free fatty acid receptor 1 (FFAR1/GPR40) protects from palmitate-induced...

Keywords:	TUG469, TUG 469
CAS	1236109-67-3
MW:	345.43 D

From 45.00€ *

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