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Item number: Cay44272-10

TUG-469 is an agonist of free fatty aid receptor 1 (FFAR1/GPR40). It induces calcium mobilization in a reporter assay using cells expressing human FFAR1/GPR40 (EC50 = 18. nM). TUG-469 (10 µM) induces insulin secretion in INS-1E insulinoma cells. It inhibits increases in blood glucose levels in a glucose tolerance...

Keywords:	4-[[(2'-methyl[1,1'-biphenyl]-3-yl)methyl]amino]-benzenepropanoic acid
Application:	FFAR1/GPR40 agonist
CAS	1236109-67-3
MW:	345.44 D

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