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ERK5-IN-1
Item number: TGM-T5184-100mg
Description: ERK5-IN-1 is a potent ERK5 inhibitor (IC50: 87 nM) and also inhibits LRRK2[G2019S] (IC50: 26 nM). Target: ERK. Smiles: COc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccccc3N(C)c2n1)N1CCN(C)CC1. References: Deng X, et al. Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of...
| Application: | ERK5 inhibitor |
| CAS | 1234479-76-5 |
| MW: | 459.54 D |
From 48.00€
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XMD8-85
Item number: Cay29662-5
XMD8-85 is an ERK5 inhibitor (IC50 = 87 nM in an enzyme assay). It is selective for ERK5 over tyrosine non-receptor kinase 2 (TNK2, IC50 = 959 nM), but does inhibit the leucine-rich repeat kinase 2 (LRRK2) mutant LRRK2G2019S (IC50 = 26 nM), which has been found in patients with Parkinson's disease. XMD8-85 inhibits...
| Keywords: | ERK5-IN-1,... |
| Application: | ERK5 inhibitor |
| CAS | 1234479-76-5 |
| MW: | 459.5 D |
From 61.00€
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