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Item number: Cay29662-5

XMD8-85 is an ERK5 inhibitor (IC50 = 87 nM in an enzyme assay). It is selective for ERK5 over tyrosine non-receptor kinase 2 (TNK2, IC50 = 959 nM), but does inhibit the leucine-rich repeat kinase 2 (LRRK2) mutant LRRK2G2019S (IC50 = 26 nM), which has been found in patients with Parkinson's disease. XMD8-85 inhibits...

Keywords:	ERK5-IN-1,...
Application:	ERK5 inhibitor
CAS	1234479-76-5
MW:	459.5 D

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