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Item number: Cay10743-1

Cytosolic phospholipase A2alpha (cPLA2alpha) specifically catalyzes the hydrolysis of arachidonic acid from the sn-2-ester position of membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes, both important mediators of the inflammatory process. CAY10650 is a...

Keywords:	3-(2-methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid
Application:	cPLA2alpha inhibitor
CAS	1233706-88-1
MW:	471.5 D

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CAY10650

Item number: TGM-TQ0105-100mg

Description: CAY10650 is an effective inhibitor of cytosolic phospholipase A2alpha (cPLA2alpha, IC50: 12 nM). Target: Phospholipase. Smiles: CC(C)C(=O)c1cn(CC(=O)COc2ccc(Oc3ccccc3)cc2)c2ccc(cc12)C(O)=O. References: Tripathi T, et al. Role of phospholipase A 2(PLA2) inhibitors in attenuating apoptosis of the corneal...

CAS	1233706-88-1
MW:	471.5 D

From 45.00€ *

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