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Item number: Cay14125-5

Clofarabine is a nucleoside analog that inhibits ribonucleotide reductase and DNA polymerase-alpha (IC50s = 65 and 3.9 nM, respectively) and is cytotoxic to K562 myelogenous leukemia cells (IC50 = 5 nM). It induces apoptosis in primary chronic lymphocytic leukemia cells by directly altering mitochondrial...

Keywords:	Clolar, Evoltra, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine
Application:	Ribonucleotide reductase and DNA polymerase-alpha Inhibitor
CAS	123318-82-1
MW:	303.7 D

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Clofarabine

Item number: LKT-C4646.10

Nucleoside (adenosine) analog, DNA chain terminator, ribonucleotide reductase and DNA polymerase inhibitor, A1/2/3 adenosine modulator.

Keywords:	(2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
Application:	Ribonucleotide reductase inhibitor
CAS	123318-82-1
MW:	303.68 D

From 238.00€ *

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