3 products were found matching "1232030-35-1"!
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FRAX486
Item number: TGM-T6840-2mg
Description: FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively. Target: PAK. Smiles: C(C)N1C=2C(C=C(C1=O)C3=C(Cl)C=C(Cl)C=C3)=CN=C(NC4=CC(F)=C(C=C4)N5CCNCC5)N2. References: Hayashi-Takagi A, et al. Proc Natl Acad Sci U S A....
| Application: | PAK1 / PAK2 / PAK3 inhibitor |
| CAS | 1232030-35-1 |
| MW: | 513.39 D |
From 37.00€
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FRAX486
Item number: Cay24682-5
FRAX486 is an inhibitor of group I p21-activated kinases (PAKs, IC50s = 8.25, 39.5, and 55.3 nM for PAK1, PAK2, and PAK3, respectively). It is selective for group I PAKs over PAK4, a group II PAK (IC50 = 779 nM). FRAX486 (20 mg/kg) reverses decreases in the mean density of apical dendritic spines in the temporal...
| Keywords: | 6-(2,4-dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]-pyrido[2,3-d]pyrimidin-7(8H)-one |
| Application: | PAK1 / PAK2 / PAK3 inhibitor |
| CAS | 1232030-35-1 |
| MW: | 513.4 D |
From 49.00€
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FRAX486
Item number: LKT-F6803.1
PAK inhibitor.Smo inhibitor.
| Application: | PAK inhibitor.Smo inhibitor |
| CAS | 1232030-35-1 |
| MW: | 522.4 D |
From 177.00€
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