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Item number: Cay10498-5

HA-130 is a reversible inhibitor of autotaxin, completely blocking the hydrolysis of the substrate bis-pNPP with an IC50 value of 28 nM. It does not affect the activity of any proteasomal protease or related enzymes. HA-130 rapidly decreases plasma lysophosphatidic acid levels in mice when given intravenously (1...

Keywords:	B-[3-[[4-[[3-[(4-fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]-boronic acid
Application:	Reversible autotaxin inhibitor
CAS	1229652-21-4
MW:	463.3 D

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HA130

Item number: TGM-T2646-100mg

Description: HA130 is a selective ATX (autotaxin) inhibitor. Target: PDE. Smiles: OB(O)c1cccc(COc2ccc(\C=C3/SC(=O)N(Cc4ccc(F)cc4)C3=O)cc2)c1. References: Zhang Y, et al. J Immunol. 2012 Oct 15,189(8):3914-3924.

CAS	1229652-21-4
MW:	463.29 D

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