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MLN0905
Item number: TGM-T2704-10mg
Description: MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM). Target: PLK. Smiles: CN(C)CCCc1cnc(C)c(Nc2ncc3CC(=S)Nc4cc(ccc4-c3n2)C(F)(F)F)c1. References: Duffey MO, et al. J Med Chem, 2012, 55(1), 197-208.
| Keywords: | PLK1 Inhibitor |
| Application: | Plk1 inhibitor |
| CAS | 1228960-69-7 |
| MW: | 486.56 D |
From 55.00€
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MLN0905
Item number: Cay31115-1
MLN0905 is an inhibitor of polo-like kinase 1 (Plk1, IC50 = 2 nM). It inhibits 95% of Plk1 activity but also inhibits the activity of 10 additional kinases by greater than or equal to 90% in a panel of 359 kinases at 1 µM. MLN0905 reduces phosphorylation of histone H3 at serine 10 (H3S10Ph), a marker of cell cycle...
| Keywords: | 2-[[5-[3-(dimethylamino)propyl]-2-methyl-3-pyridinyl]amino]-5,7-dihydro-9-(trifluoromethyl)-6H-pyrimido[5,4-d][1]benzazepi... |
| Application: | Plk1 inhibitor |
| CAS | 1228960-69-7 |
| MW: | 486.6 D |
From 69.00€
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