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Alosetron (hydrochloride)
Item number: Cay22434-25
Alosetron is an antagonist of the serotonin (5-HT) receptor subtype 5-HT3 (Kis = 0.3 and 0.4 nM for the rat cortical and human recombinant receptors, respectively). It is selective for 5-HT3 over 5-HT2 and 5-HT1A receptors (Kis = 6.3 and >100 µM, respectively), as well as alpha1-, beta1-, and beta2- adrenergic, M1,...
| Keywords: | GR 68755, 2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one, monohydrochloride |
| Application: | Serotonin 5-HT3 receptor antagonist |
| CAS | 122852-69-1 |
| MW: | 330.8 D |
From 38.00€
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Alosetron hydrochloride
Item number: TGM-T2525-10mg
Description: Alosetron hydrochloride (GR 68755) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system, particularly on enteric and nociceptive sensory neurons, thereby affecting the...
| Keywords: | GR 68755X, GR 68755, Lotronex, GR 68755C |
| Application: | Targets 5-hydroxytryptamine receptor 3 (HTR3) |
| CAS | 122852-69-1 |
| MW: | 330.81 D |
From 30.00€
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