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Item number: TGM-T16695-10mg

Description: Pyrintegrin, a beta1-integrin agonist, promotes the survival of embryonic stem cells, can be used as a podocyte-protective agent, and enhances cell-extracellular matrix adhesion-mediated integrin signaling. Target: Integrin. Smiles: Oc1ccc2N(CCCc2c1)c1ccnc(Nc2ccc(cc2)S(=O)(=O)NCC2CC2)n1. References:...

CAS	1228445-38-2
MW:	451.54 D

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Pyrintegrin

Item number: Cay16179-1

Human embryonic stem cells (hESC), unlike murine ESC, grow in vitro as large flattened two dimensional colonies. Dispersing these colonies, using trypsin to dissociate single hESC, results in massive cell death. Pyrintegrin is a 2,4-disubstituted pyrimidine that, at 2 µM, enhances the survival of hESC more than...

Keywords:	N-(cyclopropylmethyl)-4-[[4-(3,4-dihydro-6-hydroxy-1(2H)-quinolinyl)-2-pyrimidinyl]amino]-benzenesulfonamide
Application:	Human ESC trypsin-mediated dissociation survival enhancer
CAS	1228445-38-2
MW:	451.5 D

From 126.00€ *

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