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LCL521
Item number: TGM-T11835-100mg
Description: LCL521 inhibits lysosomal acid sphingomyelinase (ASMase).LCL521 is an acid ceramidase (ACDase) inhibitor. Target: Others, Phospholipase. Smiles: [C@@H]([C@H](NC(CCCCCCCCCC CCC)=O)COC(CN(C)C)=O)(OC(CN(C)C)=O)C1=CC=C(N(=O)=O)C=C1. References: Bai A, et al. Targeting (cellular) lysosomal acid ceramidase...
| Application: | Acid ceramidase inhibitor |
| CAS | 1226851-11-1 |
| MW: | 592.77 D |
From 986.00€
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LCL-521
Item number: Cay29738-1
LCL-521 is an inhibitor of acid ceramidase. It inhibits acid ceramidase activity in MCF-7 breast cancer cell lysates when used at a concentration of 1 µM. LCL-521 (1 and 10 µM) decreases sphingosine levels in MCF-7 cells. It inhibits the proliferation of MCF-7 cells (IC50 = 7.46 µM) and induces cell cycle arrest at...
| Keywords: | N,N-dimethyl-glycine, 1,1'-[(1R,2R)-1-(4-nitrophenyl)-2-[(1-oxotetradecyl)amino]-1,3-propanediyl] ester |
| Application: | Acid ceramidase inhibitor |
| CAS | 1226851-11-1 |
| MW: | 592.8 D |
From 152.00€
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