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Thiazovivin
Thiazovivin

Item number: Cay14245-1

Rho-associated kinase (ROCK) is a serine-threonine kinase known to play an important role in Rho-mediated cytoskeleton remodeling and contractile force generation. Down-regulation of ROCK signaling has been shown to enable the cell-adhesion interactions necessary for maintaining human embryonic stem cell survival...
Keywords: Tzv, N-(phenylmethyl)-2-(4-pyrimidinylamino)-4-thiazolecarboxamide
Application: Cell-permeable ROCK inhibitor
CAS 1226056-71-8
MW: 311.4 D
From 64.00€ *
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Thiazovivin
Thiazovivin

Item number: LKT-T3132.1

Thiazovivin is an inhibitor of ROCK that stabilizes E-cadherin and induces stem cell differentiation.
Application: ROCK inhibitor
CAS 1226056-71-8
MW: 311.36 D
From 90.00€ *
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Thiazovivin
Thiazovivin

Item number: TGM-T2155-100mg

Description: Thiazovivin, a ROCK inhibitor (IC50: 0.5 µM), increases the survival rate of hESC. Target: ROCK. Smiles: O=C(NCc1ccccc1)c1csc(Nc2ccncn2)n1. References: Xu Y, et al. Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc Natl Acad Sci...
CAS 1226056-71-8
MW: 311.36 D
From 30.00€ *
Review