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Item number: Cay34422-10

SKLB1002 is a VEGFR2 inhibitor (IC50 = 32 nM). It is selective for VEGFR2 over a panel of 16 additional kinases (IC50s = 619->10,000 nM). SKLB1002 inhibits tube formation, migration, and VEGF-induced proliferation of human umbilical vein endothelial cells (HUVECs). It induces tumor cell apoptosis, decreases tumor...

Keywords:	6,7-dimethoxy-4-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]-quinazoline
Application:	VEGFR2 inhibitor
CAS	1225451-84-2
MW:	320.4 D

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SKLB1002

Item number: TGM-T2421-100mg

Description: SKLB1002 is a potent and ATP-competitive VEGFR2 inhibitor with IC50 of 32 nM. Target: VEGFR. Smiles: COc1cc2ncnc(Sc3nnc(C)s3)c2cc1OC

CAS	1225451-84-2
MW:	320.39 D

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