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GSK2256098
Item number: Cay22955-1
GSK2256098 is an inhibitor of focal adhesion kinase (FAK). It is selective for FAK, inhibiting only FAK greater than 50% in a panel of 261 kinases. GSK2256098 inhibits FAK autophosphorylation at tyrosine 397 (Y397) in OVCAR8 ovarian, U87MG glioblastoma, and A549 lung cancer cell lines (IC50s = 15, 8.5, and 12 nM,...
| Keywords: | 2-[[5-chloro-2-[[3-methyl-1-(1-methylethyl)-1H-pyrazol-5-yl]amino]-4-pyridinyl]amino]-N-methoxy-benzamide |
| Application: | PTK2 inhibitor |
| CAS | 1224887-10-8 |
| MW: | 414.9 D |
From 52.00€
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GSK2256098
Item number: TGM-T2281-100mg
Description: GSK2256098 (GTPL7939) is a small molecule FAK kinase inhibitor. Target: Apoptosis, FAK. Smiles: CONC(=O)c1ccccc1Nc1cc(Nc2cc(C)nn2C(C)C)ncc1Cl. References: Zhang J, et al. Cell Cycle. 2014, 13(19):3143-9.
| Keywords: | GSK 2256098, GSK-2256098, GTPL7939 |
| CAS | 1224887-10-8 |
| MW: | 414.89 D |
From 38.00€
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