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WZB117
Item number: Cay19900-5
WZB117 is an irreversible inhibitor of glucose transporter 1 (Glut1) that blocks glucose transport in diverse cancer cells (IC50 = ~0.6 µM), reducing extracellular lactate and intracellular ATP levels. It inhibits cancer cell proliferation (IC50s = 5-10 µM), resulting in cell cycle arrest, senescence, and necrosis...
| Keywords: | Glucose Transporter Inhibitor IV, 3-hydroxy-benzoic acid, (3-fluoro-1,2-phenylene)ester |
| Application: | Glucose transport inhibitor, GLUT1 inhibitor |
| CAS | 1223397-11-2 |
| MW: | 368.3 D |
From 44.00€
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WZB117
Item number: AG-CR1-3694-M005
Glucose transporter GLUT inhibitor (GLUT4 > GLUT1 = GLUT3). Fast-acting irreversible GLUT1 inhibitor. Binds directly to GLUT1 involving three hydrogen bonds, one each with Asn34, Arg126 and Trp412. Blocks glucose transport in diverse cancer cells, reducing extracellular lactate and intracellular ATP levels and...
| Keywords: | WZB-117, 3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate) |
| Application: | GLUT inhibitor |
| CAS | 1223397-11-2 |
| MW: | 368.3 D |
From 39.00€
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WZB117
Item number: TGM-T7018-200mg
Description: WZB117 is a Glucose Transporter 1 (GLUT1) inhibitor. when IC50 of WZB117 approximate 10 µM, it inhibits lung cancer A549 cells and breast cancer MCF7 cells proliferation. Target: transporter. Smiles: Oc1cccc(c1)C(=O)Oc1cccc(F)c1OC(=O)c1cccc(O)c1. References: Liu Y, et al. Mol Cancer Ther. 2012,...
| Application: | GLUT inhibitor |
| CAS | 1223397-11-2 |
| MW: | 368.31 D |
From 41.00€
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