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Item number: Cay31232-10

ML-133 is an inward-rectifier potassium channel 2 (Kir2) inhibitor (IC50s = 1.8, 2.8, 2,9, and 2.6 µM for Kir2.1, Kir2.2, Kir2.3, and Kir2.6, respectively). It is selective for Kir2 channels over Kir1.1 and Kir4.1 channels (IC50s = 33 and 76 µM, respectively). ML-133 (10 and 30 nmol/animal) prevents the development...

Keywords:	N-[(4-methoxyphenyl)methyl]-1-naphthalenemethanamine, monohydrochloride
Application:	Kir2 channel inhibitor
CAS	1222781-70-5
MW:	313.8 D

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ML133 hydrochloride

Item number: TGM-T6592-100mg

Description: ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 µM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1. Target: Potassium Channel. Smiles: Cl.COC1=CC=C(CNCC2=CC=CC3=CC=CC=C23)C=C1. References: Wang HR, et...

Keywords:	ML133 HCl
Application:	Kir2 channel inhibitor
CAS	1222781-70-5
MW:	313.82 D

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