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Item number: TGM-T83655-100mg

Description: DLIN-MC2-DMA (DLin-M-C2-DMA) is a lipid membrane and a potential nucleic acid carrier. Target: Others. Smiles: C(OC(CCN(C)C)=O)(CCCCCCCC/C=C\C/C=C\CCCCC)CCCCCCCC/C=C\C/C=C\CCCCC. References: Michael J, et al. Improved amino lipids and methods for the delivery of nucleic acids. WO2010042877A1.

Keywords:	DLin-M-C2-DMA
CAS	1221271-55-1
MW:	628.07 D

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DLin-MC2-DMA

Item number: Cay39731-1

DLin-MC2-DMA is an ionizable cationic lipid (pKa = 5.64) that has been used in the formation of lipid nanoparticles (LNPs). LNPs containing DLin-MC2-DMA and encapsulating siRNA targeting mRNA encoding mouse coagulation Factor VII (FVII) reduce hepatic levels of FVII in mice (ED50 = 0.6 mg/kg).Formal Name:...

Keywords:	MC2, N,N-dimethyl-beta-alanine (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester
Application:	Ionizable cationic lipid, LNP formation
CAS	1221271-55-1
MW:	628.1 D

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