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DLin-MC2-DMA
DLin-MC2-DMA

Item number: Cay39731-1

DLin-MC2-DMA is an ionizable cationic lipid (pKa = 5.64) that has been used in the formation of lipid nanoparticles (LNPs). LNPs containing DLin-MC2-DMA and encapsulating siRNA targeting mRNA encoding mouse coagulation Factor VII (FVII) reduce hepatic levels of FVII in mice (ED50 = 0.6 mg/kg).Formal Name:...
Keywords: MC2, N,N-dimethyl-beta-alanine (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester
Application: Ionizable cationic lipid, LNP formation
CAS 1221271-55-1
MW: 628.1 D
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