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SR 7826
Item number: Cay32976-10
SR 7826 is an inhibitor of LIM kinase 1 (LIMK1, IC50 = 43 nM). It is selective for LIMK1 over Rho-associated kinase 1 (ROCK1) and ROCK2 (IC50s = 6,565 and 5,536 nM, respectively) and a panel of 60 kinases at 1 µM but does inhibit serine/threonine kinase 16 (STK16) by greater than 80% at 1 µM. SR 7826 inhibits the...
| Keywords: | N-(2-hydroxyethyl)-N'-[4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]-N-phenyl-urea |
| Application: | LIMK1 inhibitor |
| CAS | 1219728-20-7 |
| MW: | 387.43 D |
From 229.00€
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SR7826
Item number: TGM-T26224-100mg
Description: SR7826 is a selective LIMK inhibitor. Target: Others. Smiles: Cc1c[nH]c2ncnc(-c3ccc(NC(=O)N(CCO)c4ccccc4)cc3)c12. References: Yu Q, Gratzke C, Wang Y, Herlemann A, Sterr CM, Rutz B, Ciotkowska A, Wang X, Strittmatter F, Stief CG, Hennenberg M. Inhibition of human prostate smooth muscle contraction by...
| Keywords: | SR 7826, SR-7826 |
| CAS | 1219728-20-7 |
| MW: | 387.43 D |
From 616.00€
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