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Item number: TGM-TQ0051-10mg

Description: MK-7246 is a potent and specific CRTH2 antagonist (Ki: 2.5 nM). Target: GPR. Smiles: CN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)S(=O)(=O)c1ccc(F)cc1. References: Gervais FG, et al. Pharmacological characterization of MK-7246, a potent and selective CRTH2 (chemoattractant receptor-homologous molecule expressed...

Application:	CRTH2/DP2 receptor antagonist
CAS	1218918-62-7
MW:	416.47 D

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MK-7246

Item number: Cay34208-1

MK-7246 is an antagonist of the prostaglandin D2 (PGD2, Cay-12010) receptor CRTH2/DP2 (Ki = 2.5 nM). It is selective for CRTH2/DP2 over DP1, the PGF2alpha receptor (FP), the PGI2 receptor (IP), and the thromboxane A2 (TP) receptor (Kis = 373, >25,100, >23,030, and 3,804 nM, respectively), as well as the PGE2...

Keywords:	(7R)-7-[[(4-fluorophenyl)sulfonyl]methylamino]-6,7,8,9-tetrahydro-pyrido[1,2-a]indole-10-acetic acid
Application:	CRTH2/DP2 receptor antagonist
CAS	1218918-62-7
MW:	416.5 D

From 87.00€ *

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