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Item number: Cay42733-1

BX-513 is an antagonist of chemokine (C-C motif) receptor 1 (CCR1, Ki = 0. µM). It is selective for CCR1 over 15 other receptors (Kis = 2->10 µM). BX-513 inhibits increases in acidification induced by chemokine (C-C motif) ligand 18 (CCL18) in THP-1 monocytes in a concentration-dependent manner. It inhibits RANTES-...

Keywords:	VUF 2274, 4-(4-chlorophenyl)-4-hydroxy-a,a-diphenyl-1-piperidinepentanenitrile, monohydrochloride
Application:	CCR1 antagonist
CAS	1216540-18-9
MW:	481.46 D

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