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Item number: Cay18862-1

MMPIP is a reversible allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7) that blocks agonist-induced calcium mobilization (IC50 = 26 nM). It does not affect other mGlu receptors. The modulation of mGluR7 by MMPIP is context dependent, in that it is not observed in all known mGluR7 signaling...

Keywords:	6-(4-methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[4,5-c]pyridin-4(5H)-one, monohydrochloride
Application:	mGluR7 antagonist
CAS	1215566-78-1
MW:	369.8 D

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MMPIP hydrochloride

Item number: TGM-T23008L-100mg

Description: MMPIP hydrochloride is a selective antagonist of allosteric mGluR7. MMPIP hydrochloride can be used in research on the roles of mGluR7 on central nervous system functions. Target: GluR. Smiles: Cl.COc1ccc(cc1)-c1cc2onc(-c3ccncc3)c2c(=O)n1C. References: Gentaroh Suzuki, et al. In vitro pharmacological...

Keywords:	MMPIP hydrochloride (479077-02-6 Free base)
CAS	1215566-78-1
MW:	369.8 D

From 55.00€ *

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