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Item number: Cay21568-5

RGFP109 is a brain-penetrant inhibitor of histone deacetylases (HDACs, IC50s = 60 and 50 nM, Kis = 32 and 5 nM for HDAC1 and HDAC3 in cell-free assays, respectively). It has been shown to upregulate frataxin mRNA levels in cultured cells obtained from Friedreich's ataxia patients and in a GAA repeat-based mouse...

Keywords:	RG-2833, N-[6-[(2-aminophenyl)amino]-6-oxohexyl]-4-methyl-benzamide
Application:	Brain-penetrant HDAC inhibitor
CAS	1215493-56-3
MW:	339.4 D

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RG2833

Item number: TGM-T6639-100mg

Description: RG2833 (RGFP109) (RGFP109), a brain-penetrant HDAC inhibitor, is with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3, respectively. Target: HDAC. Smiles: Cc1ccc(cc1)C(=O)NCCCCCC(=O)Nc1ccccc1N. References: Rai M, et al. PLoS One. 2010, 5(1), e8825.

Keywords:	RGFP109
Application:	Brain-penetrant HDAC inhibitor
CAS	1215493-56-3
MW:	339.43 D

From 30.00€ *

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